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Oral Vaccination With Recombinant Vesicular Stomatitis Virus Expressing Sin Nombre Virus Glycoprotein Prevents Sin Nombre Virus Transmission in Deer Mice

Sin Nombre virus (SNV) is the major cause of hantavirus cardiopulmonary syndrome (HCPS) in North America, a severe respiratory disease with a high fatality rate. SNV is carried by Peromyscus maniculatus, or deer mice, and human infection occurs following inhalation of aerosolized virus in mouse excr...

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Detalles Bibliográficos
Autores principales: Warner, Bryce M., Jangra, Rohit K., Griffin, Bryan D., Stein, Derek R., Kobasa, Darwyn, Chandran, Kartik, Kobinger, Gary P., Safronetz, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7360791/
https://www.ncbi.nlm.nih.gov/pubmed/32733817
http://dx.doi.org/10.3389/fcimb.2020.00333