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Tolerability, Safety, Pharmacokinetics and Drug Interaction of Cefotaxime Sodium–Tazobactam Sodium Injection (6:1) Following Single and Multiple Intravenous Doses in Chinese Healthy Subjects

PURPOSE: To evaluate the tolerability, safety, pharmacokinetics and drug interaction of cefotaxime sodium–tazobactam sodium injection (6:1) in Chinese healthy subjects. The results of the safety and pharmacokinetic studies supported further clinical trials. METHOD: A randomized, single-blind, ascend...

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Detalles Bibliográficos
Autores principales: Chen, Ning, Sun, Lu-Ning, Hu, Wen-Hui, Wang, Yi-Ya, Xie, Li-Jun, Cheng, Juan, Zhang, Hong-Wen, Liu, Yun, Wang, Yong-Qing, Ding, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7360824/
https://www.ncbi.nlm.nih.gov/pubmed/32733255
http://dx.doi.org/10.3389/fphar.2020.01033