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In vitro IL-6/IL-6R Trans-Signaling in Fibroblasts Releases Cytokines That May Be Linked to the Pathogenesis of IgG4-Related Disease

Background: The remarkable mechanisms of storiform fibrosis and the formation of high levels of IgG4 with a pathogenic germinal center (GC) in the inflammatory tissue of IgG4-RD remains unknown and may be responsible for the unsatisfactory therapeutic effect on IgG4-related diseases when using conve...

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Detalles Bibliográficos
Autores principales: Zongfei, Ji, Rongyi, Chen, Xiaomeng, Cui, Lili, Ma, Lingying, Ma, Xiufang, Kong, Xiaomin, Dai, Zhuojun, Zhang, Huiyong, Chen, Ying, Sun, Lindi, Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7360847/
https://www.ncbi.nlm.nih.gov/pubmed/32733444
http://dx.doi.org/10.3389/fimmu.2020.01272