Mining and fine-tuning sugar uptake system for titer improvement of milbemycins in Streptomyces bingchenggensis

Dramatic decrease of sugar uptake is a general phenomenon in Streptomyces at stationary phase, when antibiotics are extensively produced. Milbemycins produced by Streptomyces bingchenggensis are a group of valuable macrolide biopesticides, while the low yield and titer impede their broad application...

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Detalles Bibliográficos
Autores principales: Jin, Pinjiao, Li, Shanshan, Zhang, Yanyan, Chu, Liyang, He, Hairong, Dong, Zhuoxu, Xiang, Wensheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7360889/
https://www.ncbi.nlm.nih.gov/pubmed/32695892
http://dx.doi.org/10.1016/j.synbio.2020.07.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7360889/
https://www.ncbi.nlm.nih.gov/pubmed/32695892
http://dx.doi.org/10.1016/j.synbio.2020.07.001

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