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Conditional DnaB Protein Splicing Is Reversibly Inhibited by Zinc in Mycobacteria

Inteins, as posttranslational regulatory elements, can tune protein function to environmental changes by conditional protein splicing (CPS). Translated as subdomains interrupting host proteins, inteins splice to scarlessly join flanking sequences (exteins). We used DnaB-intein1 (DnaBi1) from a repli...

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Detalles Bibliográficos
Autores principales: Woods, Daniel, Vangaveti, Sweta, Egbanum, Ikechukwu, Sweeney, Allison M., Li, Zhong, Bacot-Davis, Valjean, LeSassier, Danielle S., Stanger, Matthew, Hardison, Gabrielle E., Li, Hongmin, Belfort, Marlene, Lennon, Christopher W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7360933/
https://www.ncbi.nlm.nih.gov/pubmed/32665276
http://dx.doi.org/10.1128/mBio.01403-20