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Auto‐inhibition of Mif2/CENP‐C ensures centromere‐dependent kinetochore assembly in budding yeast

Kinetochores are chromatin‐bound multi‐protein complexes that allow high‐fidelity chromosome segregation during mitosis and meiosis. Kinetochore assembly is exclusively initiated at chromatin containing Cse4/CENP‐A nucleosomes. The molecular mechanisms ensuring that subcomplexes assemble efficiently...

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Detalles Bibliográficos
Autores principales: Killinger, Kerstin, Böhm, Miriam, Steinbach, Philine, Hagemann, Götz, Blüggel, Mike, Jänen, Karolin, Hohoff, Simone, Bayer, Peter, Herzog, Franz, Westermann, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7360964/
https://www.ncbi.nlm.nih.gov/pubmed/32515113
http://dx.doi.org/10.15252/embj.2019102938