Dysfunctional oxidative phosphorylation shunts branched‐chain amino acid catabolism onto lipogenesis in skeletal muscle

It is controversial whether mitochondrial dysfunction in skeletal muscle is the cause or consequence of metabolic disorders. Herein, we demonstrate that in vivo inhibition of mitochondrial ATP synthase in muscle alters whole‐body lipid homeostasis. Mice with restrained mitochondrial ATP synthase act...

Descripción completa

Detalles Bibliográficos
Autores principales: Sánchez‐González, Cristina, Nuevo‐Tapioles, Cristina, Herrero Martín, Juan Cruz, Pereira, Marta P, Serrano Sanz, Sandra, Ramírez de Molina, Ana, Cuezva, José M, Formentini, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7360968/
https://www.ncbi.nlm.nih.gov/pubmed/32488939
http://dx.doi.org/10.15252/embj.2019103812

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7360968/
https://www.ncbi.nlm.nih.gov/pubmed/32488939
http://dx.doi.org/10.15252/embj.2019103812

Ejemplares similares