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Tackling COVID‐19 infection through complement‐targeted immunotherapy

The complement system is an ancient part of innate immunity sensing highly pathogenic coronaviruses by mannan‐binding lectin (MBL) resulting in lectin pathway activation and subsequent generation of the anaphylatoxins (ATs) C3a and C5a as important effector molecules. Complement deposition on endoth...

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Detalles Bibliográficos
Autores principales: Jodele, Sonata, Köhl, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7361469/
https://www.ncbi.nlm.nih.gov/pubmed/32643798
http://dx.doi.org/10.1111/bph.15187