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Thiopurine S-methyltransferase genetic polymorphisms in adult patients with inflammatory bowel diseases in the Latvian population

BACKGROUND: Thiopurine methyltransferase (TPMT) plays a significant role in the metabolism of thiopurines, and, for patients with inflammatory bowel disease (IBD), it is useful to perform TPMT genotyping prior to azathioprine (AZA) treatment. In this study, we determined TPMT gene polymorphisms in a...

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Detalles Bibliográficos
Autores principales: Zalizko, Polina, Stefanovics, Juris, Sokolovska, Jelizaveta, Paramonova, Natalia, Klavina, Evija, Erts, Renars, Rovite, Vita, Klovins, Janis, Pukitis, Aldis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7361485/
https://www.ncbi.nlm.nih.gov/pubmed/32704308
http://dx.doi.org/10.1177/1756284820937426