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If it’s not one thing, HIF’s another: immunoregulation by hypoxia inducible factors in disease

Hypoxia‐inducible factors (HIFs) have emerged in recent years as critical regulators of immunity. Localised, low oxygen tension is a hallmark of inflamed and infected tissues. Subsequent myeloid cell HIF stabilisation plays key roles in the innate immune response, alongside emerging oxygen‐independe...

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Detalles Bibliográficos
Autores principales: Hammond, Ffion R., Lewis, Amy, Elks, Philip M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7362030/
https://www.ncbi.nlm.nih.gov/pubmed/32633061
http://dx.doi.org/10.1111/febs.15476