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The sputum microbiome is distinct between COPD and health, independent of smoking history

BACKGROUND: Airway bacterial dysbiosis is a feature of chronic obstructive pulmonary disease (COPD). However, there is limited comparative data of the lung microbiome between healthy smokers, non-smokers and COPD. METHODS: We compared the 16S rRNA gene-based sputum microbiome generated from pair-end...

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Detalles Bibliográficos
Autores principales: Haldar, Koirobi, George, Leena, Wang, Zhang, Mistry, Vijay, Ramsheh, Mohammadali Yavari, Free, Robert C., John, Catherine, Reeve, Nicola F., Miller, Bruce E., Tal-Singer, Ruth, Webb, Adam J., Brookes, Anthony J., Tobin, Martin D., Singh, Dave, Donaldson, Gavin C., Wedzicha, Jadwiga A., Brown, James R., Barer, Michael R., Brightling, Christopher E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7362436/
https://www.ncbi.nlm.nih.gov/pubmed/32664956
http://dx.doi.org/10.1186/s12931-020-01448-3