Fyn depletion ameliorates tau(P301L)-induced neuropathology

The Src family non-receptor tyrosine kinase Fyn has been implicated in neurodegeneration of Alzheimer’s disease through interaction with amyloid β (Aβ). However, the role of Fyn in the pathogenesis of primary tauopathies such as FTDP-17, where Aβ plaques are absent, is poorly understood. In the curr...

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Detalles Bibliográficos
Autores principales: Liu, Guanghao, Fiock, Kimberly L., Levites, Yona, Golde, Todd E., Hefti, Marco M., Lee, Gloria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7362472/
https://www.ncbi.nlm.nih.gov/pubmed/32665013
http://dx.doi.org/10.1186/s40478-020-00979-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7362472/
https://www.ncbi.nlm.nih.gov/pubmed/32665013
http://dx.doi.org/10.1186/s40478-020-00979-6

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