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An unlabelled probe-based real time PCR and modified semi-nested PCR as molecular tools for analysis of chloroquine resistant Plasmodium vivax isolates from Afghanistan

BACKGROUND: Plasmodium vivax resistance to chloroquine (CQ) has been reported from many endemic regions in the world. Plasmodium vivax is responsible for 95% of malaria cases in Afghanistan and CQ is the first-line treatment given for vivax malaria. The pvmdr-1 and pvcrt-o (K10 insertion) genes are...

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Detalles Bibliográficos
Autores principales: Mosawi, Sayed Hussain, Dalimi, Abdolhossein, Safi, Najibullah, Fotouhi-Ardakani, Reza, Ghaffarifar, Fatemeh, Sadraei, Javid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7362495/
https://www.ncbi.nlm.nih.gov/pubmed/32664942
http://dx.doi.org/10.1186/s12936-020-03323-4