Beyond thrombosis: the impact of tissue factor signaling in cancer

Tissue factor (TF) is the primary initiator of the coagulation cascade, though its effects extend well beyond hemostasis. When TF binds to Factor VII, the resulting TF:FVIIa complex can proteolytically cleave transmembrane G protein-coupled protease-activated receptors (PARs). In addition to activat...

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Detalles Bibliográficos
Autores principales: Unruh, Dusten, Horbinski, Craig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7362520/
https://www.ncbi.nlm.nih.gov/pubmed/32665005
http://dx.doi.org/10.1186/s13045-020-00932-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7362520/
https://www.ncbi.nlm.nih.gov/pubmed/32665005
http://dx.doi.org/10.1186/s13045-020-00932-z

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