Receptor-interacting protein kinase 1 (RIPK1) as a therapeutic target

Receptor-interacting serine/threonine-protein kinase 1 (RIPK1) is a key mediator of cell death and inflammation. The unique hydrophobic pocket in the allosteric regulatory domain of RIPK1 has enabled the development of highly selective small-molecule inhibitors of its kinase activity, which have dem...

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Detalles Bibliográficos
Autores principales: Mifflin, Lauren, Ofengeim, Dimitry, Yuan, Junying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7362612/
https://www.ncbi.nlm.nih.gov/pubmed/32669658
http://dx.doi.org/10.1038/s41573-020-0071-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7362612/
https://www.ncbi.nlm.nih.gov/pubmed/32669658
http://dx.doi.org/10.1038/s41573-020-0071-y

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