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Relationship between the temporal course of astrogliosis and symptom improvement in cerebral infarction: report of a case monitored using (18)F-THK5351 positron emission tomography

BACKGROUND: (18)F-THK5351 was recently shown to bind to monoamine oxidase B (MAO-B) with high affinity. MAO-B is highly concentrated in astrocytes and increases during astrogliosis. Therefore, (18)F-THK5351 accumulates in lesions undergoing astrogliosis. Cerebral infarction causes astrogliosis, whic...

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Detalles Bibliográficos
Autores principales: Ishibashi, Kenji, Miura, Yoshiharu, Hirata, Kosei, Toyohara, Jun, Ishii, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7362635/
https://www.ncbi.nlm.nih.gov/pubmed/32664871
http://dx.doi.org/10.1186/s12880-020-00481-4