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Decreased expression of interferon‐stimulated genes in B cells of patients with chronic hepatitis C during interferon‐free therapy potentially suggests the eradication of hepatitis C virus in the B cells: A cohort study

AIMS: Hepatitis C virus (HCV) infection is monitored by the host innate immunity that includes the endogenous interferon (IFN), which up‐regulates IFN‐stimulated genes (ISGs). HCV is both hepatotropic and lymphotropic, but HCV replication in lymphoid cells is a controversial issue. Here, we analyzed...

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Detalles Bibliográficos
Autores principales: Arai, Jun, Ito, Takayoshi, Shimozuma, Yuu, Uchikoshi, Manabu, Nakajima, Yoko, Sakaki, Masashi, Uozumi, Shojiro, Kajiwara, Atsushi, Sugiura, Ikuya, Otoyama, Yumi, Nozawa, Hisako, Kurihara, Toshikazu, Eguchi, Junichi, Nomura, Norihiro, Sakuma, Dai, Sato, Masashi, Deguchi, Yoshio, Yoshida, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7362757/
https://www.ncbi.nlm.nih.gov/pubmed/32685701
http://dx.doi.org/10.1002/hsr2.176