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A multicenter consensus: A role of furin in the endothelial tropism in obese patients with COVID-19 infection

Furin, a cleavage enzyme, is increasingly recognized in the pathogenesis of metabolic syndrome. Its cleavage action is an essential activation step for the endothelial pathogenicity of several viruses including SARS-CoV-2. This Furin-mediated endothelial tropism seems to underlie the multi-organ sys...

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Detalles Bibliográficos
Autores principales: AbdelMassih, Antoine Fakhry, Ye, Jianping, Kamel, Aya, Mishriky, Fady, Ismail, Habiba-Allah, Ragab, Heba Amin, El Qadi, Layla, Malak, Lauris, Abdu, Mariam, El-Husseiny, Miral, Ashraf, Mirette, Hafez, Nada, AlShehry, Nada, El-Husseiny, Nadine, AbdelRaouf, Nora, Shebl, Noura, Hafez, Nouran, Youssef, Nourhan, Afdal, Peter, Hozaien, Rafeef, Menshawey, Rahma, Saeed, Rana, Fouda, Raghda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7362855/
https://www.ncbi.nlm.nih.gov/pubmed/32835124
http://dx.doi.org/10.1016/j.obmed.2020.100281