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Development of Spherical Nucleic Acids for Prostate Cancer Immunotherapy

Although the strategy of therapeutic vaccination for the treatment of prostate cancer has advanced to and is available in the clinic (Sipuleucel-T), the efficacy of such therapy remains limited. Here, we develop Immunostimulatory Spherical Nucleic Acid (IS-SNA) nanostructures comprised of CpG oligon...

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Detalles Bibliográficos
Autores principales: Qin, Lei, Wang, Shuya, Dominguez, Donye, Long, Alan, Chen, Siqi, Fan, Jie, Ahn, Jihae, Skakuj, Kacper, Huang, Ziyin, Lee, Andrew, Mirkin, Chad, Zhang, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7362897/
https://www.ncbi.nlm.nih.gov/pubmed/32733447
http://dx.doi.org/10.3389/fimmu.2020.01333