Repertoire characterization and validation of gB-specific human IgGs directly cloned from humanized mice vaccinated with dendritic cells and protected against HCMV

Human cytomegalovirus (HCMV) causes serious complications to immune compromised hosts. Dendritic cells (iDCgB) expressing granulocyte-macrophage colony-stimulating factor, interferon-alpha and HCMV-gB were developed to promote de novo antiviral adaptive responses. Mice reconstituted with a human imm...

Descripción completa

Detalles Bibliográficos
Autores principales: Theobald, Sebastian J., Kreer, Christoph, Khailaie, Sahamoddin, Bonifacius, Agnes, Eiz-Vesper, Britta, Figueiredo, Constanca, Mach, Michael, Backovic, Marija, Ballmaier, Matthias, Koenig, Johannes, Olbrich, Henning, Schneider, Andreas, Volk, Valery, Danisch, Simon, Gieselmann, Lutz, Ercanoglu, Meryem Seda, Messerle, Martin, von Kaisenberg, Constantin, Witte, Torsten, Klawonn, Frank, Meyer-Hermann, Michael, Klein, Florian, Stripecke, Renata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7363084/
https://www.ncbi.nlm.nih.gov/pubmed/32667948
http://dx.doi.org/10.1371/journal.ppat.1008560

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7363084/
https://www.ncbi.nlm.nih.gov/pubmed/32667948
http://dx.doi.org/10.1371/journal.ppat.1008560

Ejemplares similares