An aberrantly sustained emergency granulopoiesis response accelerates postchemotherapy relapse in MLL1-rearranged acute myeloid leukemia in mice

Acute myeloid leukemia (AML) with mixed lineage leukemia 1 (MLL1) gene rearrangement is characterized by increased expression of a set of homeodomain transcription factors, including homeobox A9 (HOXA9) and HOXA10. The target genes for these regulators include fibroblast growth factor 2 (FGF2) and A...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Hao, Shah, Chirag A., Hu, Liping, Huang, Weiqi, Platanias, Leonidas C., Eklund, Elizabeth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Molecular Bases of Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7363149/
https://www.ncbi.nlm.nih.gov/pubmed/32467231
http://dx.doi.org/10.1074/jbc.RA120.013206

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7363149/
https://www.ncbi.nlm.nih.gov/pubmed/32467231
http://dx.doi.org/10.1074/jbc.RA120.013206

Ejemplares similares