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An aberrantly sustained emergency granulopoiesis response accelerates postchemotherapy relapse in MLL1-rearranged acute myeloid leukemia in mice

Acute myeloid leukemia (AML) with mixed lineage leukemia 1 (MLL1) gene rearrangement is characterized by increased expression of a set of homeodomain transcription factors, including homeobox A9 (HOXA9) and HOXA10. The target genes for these regulators include fibroblast growth factor 2 (FGF2) and A...

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Detalles Bibliográficos
Autores principales:	Wang, Hao, Shah, Chirag A., Hu, Liping, Huang, Weiqi, Platanias, Leonidas C., Eklund, Elizabeth A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2020
Materias:	Molecular Bases of Disease
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7363149/ https://www.ncbi.nlm.nih.gov/pubmed/32467231 http://dx.doi.org/10.1074/jbc.RA120.013206

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