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5-HT(2A) receptor loss does not alter acute fluoxetine-induced anxiety and exhibit sex-dependent regulation of cortical immediate early gene expression

Background: Acute treatment with the selective serotonin reuptake inhibitor (SSRI), fluoxetine (Flx), induces anxiety-like behavioral effects. The serotonin(2A) receptor (5-HT(2A)) is implicated in the modulation of anxiety-like behavior, however its contribution to the anxiogenic effects of acute F...

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Detalles Bibliográficos
Autores principales: Jaggar, Minal, Banerjee, Toshali, Weisstaub, Noelia, Gingrich, Jay A., Vaidya, Vidita A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7363295/
https://www.ncbi.nlm.nih.gov/pubmed/32714597
http://dx.doi.org/10.1042/NS20180205