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Distinct signals in medial and lateral VTA dopamine neurons modulate fear extinction at different times

Dopamine (DA) neurons are thought to encode reward prediction error (RPE), in addition to other signals, such as salience. While RPE is known to support learning, the role of salience in learning remains less clear. To address this, we recorded and manipulated VTA DA neurons in mice during fear exti...

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Detalles Bibliográficos
Autores principales: Cai, Lili X, Pizano, Katherine, Gundersen, Gregory W, Hayes, Cameron L, Fleming, Weston T, Holt, Sebastian, Cox, Julia M, Witten, Ilana B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7363446/
https://www.ncbi.nlm.nih.gov/pubmed/32519951
http://dx.doi.org/10.7554/eLife.54936