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Acute Inflammation Alters Brain Energy Metabolism in Mice and Humans: Role in Suppressed Spontaneous Activity, Impaired Cognition, and Delirium

Systemic infection triggers a spectrum of metabolic and behavioral changes, collectively termed sickness behavior, which while adaptive, can affect mood and cognition. In vulnerable individuals, acute illness can also produce profound, maladaptive, cognitive dysfunction including delirium, but our u...

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Detalles Bibliográficos
Autores principales: Kealy, John, Murray, Carol, Griffin, Eadaoin W., Lopez-Rodriguez, Ana Belen, Healy, Dáire, Tortorelli, Lucas Silva, Lowry, John P., Watne, Leiv Otto, Cunningham, Colm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7363463/
https://www.ncbi.nlm.nih.gov/pubmed/32513828
http://dx.doi.org/10.1523/JNEUROSCI.2876-19.2020