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Chemogenetic Modulation and Single-Photon Calcium Imaging in Anterior Cingulate Cortex Reveal a Mechanism for Effort-Based Decisions

The ACC is implicated in effort exertion and choices based on effort cost, but it is still unclear how it mediates this cost-benefit evaluation. Here, male rats were trained to exert effort for a high-value reward (sucrose pellets) in a progressive ratio lever-pressing task. Trained rats were then t...

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Detalles Bibliográficos
Autores principales: Hart, Evan E., Blair, Garrett J., O'Dell, Thomas J., Blair, Hugh T., Izquierdo, Alicia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7363467/
https://www.ncbi.nlm.nih.gov/pubmed/32527984
http://dx.doi.org/10.1523/JNEUROSCI.2548-19.2020