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A HIF1a-Dependent Pro-Oxidant State Disrupts Synaptic Plasticity and Impairs Spatial Memory in Response to Intermittent Hypoxia

Sleep apnea causes cognitive deficits and is associated with several neurologic diseases. Intermittent hypoxia (IH) is recognized as a principal mediator of pathophysiology associated with sleep apnea, yet the basis by which IH contributes to impaired cognition remains poorly defined. Using a mouse...

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Detalles Bibliográficos
Autores principales: Arias-Cavieres, Alejandra, Khuu, Maggie A., Nwakudu, Chinwendu U., Barnard, Jasmine E., Dalgin, Gokhan, Garcia, Alfredo J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7363479/
https://www.ncbi.nlm.nih.gov/pubmed/32493757
http://dx.doi.org/10.1523/ENEURO.0024-20.2020