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A HIF1a-Dependent Pro-Oxidant State Disrupts Synaptic Plasticity and Impairs Spatial Memory in Response to Intermittent Hypoxia
Sleep apnea causes cognitive deficits and is associated with several neurologic diseases. Intermittent hypoxia (IH) is recognized as a principal mediator of pathophysiology associated with sleep apnea, yet the basis by which IH contributes to impaired cognition remains poorly defined. Using a mouse...
Autores principales: | Arias-Cavieres, Alejandra, Khuu, Maggie A., Nwakudu, Chinwendu U., Barnard, Jasmine E., Dalgin, Gokhan, Garcia, Alfredo J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Neuroscience
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7363479/ https://www.ncbi.nlm.nih.gov/pubmed/32493757 http://dx.doi.org/10.1523/ENEURO.0024-20.2020 |
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