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Sequential role of RAD51 paralog complexes in replication fork remodeling and restart

Homologous recombination (HR) factors were recently implicated in DNA replication fork remodeling and protection. While maintaining genome stability, HR-mediated fork remodeling promotes cancer chemoresistance, by as-yet elusive mechanisms. Five HR cofactors – the RAD51 paralogs RAD51B, RAD51C, RAD5...

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Detalles Bibliográficos
Autores principales: Berti, Matteo, Teloni, Federico, Mijic, Sofija, Ursich, Sebastian, Fuchs, Jevgenij, Palumbieri, Maria Dilia, Krietsch, Jana, Schmid, Jonas A., Garcin, Edwige B., Gon, Stéphanie, Modesti, Mauro, Altmeyer, Matthias, Lopes, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7363682/
https://www.ncbi.nlm.nih.gov/pubmed/32669601
http://dx.doi.org/10.1038/s41467-020-17324-z