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Optical Interrogation of Sympathetic Neuronal Effects on Macroscopic Cardiomyocyte Network Dynamics

Cardiac stimulation via sympathetic neurons can potentially trigger arrhythmias. We present approaches to study neuron-cardiomyocyte interactions involving optogenetic selective probing and all-optical electrophysiology to measure activity in an automated fashion. Here we demonstrate the utility of...

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Detalles Bibliográficos
Autores principales: Burton, Rebecca-Ann B., Tomek, Jakub, Ambrosi, Christina M., Larsen, Hege E., Sharkey, Amy R., Capel, Rebecca A., Corbett, Alexander D., Bilton, Samuel, Klimas, Aleksandra, Stephens, Guy, Cremer, Maegan, Bose, Samuel J., Li, Dan, Gallone, Giuseppe, Herring, Neil, Mann, Edward O., Kumar, Abhinav, Kramer, Holger, Entcheva, Emilia, Paterson, David J., Bub, Gil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7363704/
https://www.ncbi.nlm.nih.gov/pubmed/32674058
http://dx.doi.org/10.1016/j.isci.2020.101334