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Optical Interrogation of Sympathetic Neuronal Effects on Macroscopic Cardiomyocyte Network Dynamics
Cardiac stimulation via sympathetic neurons can potentially trigger arrhythmias. We present approaches to study neuron-cardiomyocyte interactions involving optogenetic selective probing and all-optical electrophysiology to measure activity in an automated fashion. Here we demonstrate the utility of...
Autores principales: | Burton, Rebecca-Ann B., Tomek, Jakub, Ambrosi, Christina M., Larsen, Hege E., Sharkey, Amy R., Capel, Rebecca A., Corbett, Alexander D., Bilton, Samuel, Klimas, Aleksandra, Stephens, Guy, Cremer, Maegan, Bose, Samuel J., Li, Dan, Gallone, Giuseppe, Herring, Neil, Mann, Edward O., Kumar, Abhinav, Kramer, Holger, Entcheva, Emilia, Paterson, David J., Bub, Gil |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7363704/ https://www.ncbi.nlm.nih.gov/pubmed/32674058 http://dx.doi.org/10.1016/j.isci.2020.101334 |
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