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A STING-based biosensor affords broad cyclic dinucleotide detection within single living eukaryotic cells
Cyclic dinucleotides (CDNs) are second messengers conserved across all three domains of life. Within eukaryotes they mediate protective roles in innate immunity against malignant, viral, and bacterial disease, and exert pathological effects in autoimmune disorders. Despite their ubiquitous role in d...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7363834/ https://www.ncbi.nlm.nih.gov/pubmed/32669552 http://dx.doi.org/10.1038/s41467-020-17228-y |