The discovery of a new antibody for BRIL-fused GPCR structure determination

G-protein-coupled receptors (GPCRs)—the largest family of cell-surface membrane proteins—mediate the intracellular signal transduction of many external ligands. Thus, GPCRs have become important drug targets. X-ray crystal structures of GPCRs are very useful for structure-based drug design (SBDD). H...

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Detalles Bibliográficos
Autores principales: Miyagi, Hikaru, Asada, Hidetsugu, Suzuki, Michihiko, Takahashi, Yuichi, Yasunaga, Mai, Suno, Chiyo, Iwata, So, Saito, Jun-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7363855/
https://www.ncbi.nlm.nih.gov/pubmed/32669569
http://dx.doi.org/10.1038/s41598-020-68355-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7363855/
https://www.ncbi.nlm.nih.gov/pubmed/32669569
http://dx.doi.org/10.1038/s41598-020-68355-x

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