Chromatin Complexes Maintain Self-Renewal of Myeloid Progenitors in AML: Opportunities for Therapeutic Intervention

Specific subgroups of acute myeloid leukemia (AML), including those containing MLL rearrangements and NPM1c mutations, possess characteristic stem cell-like gene expression profiles. These expression programs are highly dependent on components of the MLL histone methyltransferase complex, including...

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Detalles Bibliográficos
Autores principales: Uckelmann, Hannah J., Armstrong, Scott A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7363875/
https://www.ncbi.nlm.nih.gov/pubmed/32559456
http://dx.doi.org/10.1016/j.stemcr.2020.05.013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7363875/
https://www.ncbi.nlm.nih.gov/pubmed/32559456
http://dx.doi.org/10.1016/j.stemcr.2020.05.013

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