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The TLR9 ligand CpG ODN 2006 is a poor adjuvant for the induction of de novo CD8(+) T-cell responses in vitro

Toll-like receptor 9 (TLR9) agonists have gained traction in recent years as potential adjuvants for the induction of adaptive immune responses. It has nonetheless remained unclear to what extent such ligands can facilitate the priming events that generate antigen-specific effector and/or memory CD8...

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Detalles Bibliográficos
Autores principales: Papagno, Laura, Kuse, Nozomi, Lissina, Anna, Gostick, Emma, Price, David A., Appay, Victor, Nicoli, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7363897/
https://www.ncbi.nlm.nih.gov/pubmed/32669577
http://dx.doi.org/10.1038/s41598-020-67704-0