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Development of Natural-Based Bone Cement for a Controlled Doxorubicin-Drug Release

Osteosarcoma (OS) accounts for 60% of all global bone cancer diagnoses. Intravenous administration of Doxorubicin Hydrochloride (DOXO) is the current form of OS treatment, however, systemic delivery has been linked to the onset of DOXO induced cardiomyopathy. Biomaterials including calcium phosphate...

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Detalles Bibliográficos
Autores principales: Dewhurst, Rebecca Marie, Scalzone, Annachiara, Buckley, Joseph, Mattu, Clara, Rankin, Kenneth S., Gentile, Piergiorgio, Ferreira, Ana Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7363953/
https://www.ncbi.nlm.nih.gov/pubmed/32733869
http://dx.doi.org/10.3389/fbioe.2020.00754