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Increased Dendritic Branching of and Reduced δ-GABA(A) Receptor Expression on Parvalbumin-Positive Interneurons Increase Inhibitory Currents and Reduce Synaptic Plasticity at Puberty in Female Mouse CA1 Hippocampus

Parvalbumin positive (PV+) interneurons play a pivotal role in cognition and are known to be regulated developmentally and by ovarian hormones. The onset of puberty represents the end of a period of optimal learning when impairments in synaptic plasticity are observed in the CA1 hippocampus of femal...

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Detalles Bibliográficos
Autores principales: Shen, Hui, Kenney, Lindsay, Smith, Sheryl S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7363981/
https://www.ncbi.nlm.nih.gov/pubmed/32733208
http://dx.doi.org/10.3389/fncel.2020.00203