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Integrated Pathways of COX-2 and mTOR: Roles in Cell Sensing and Alzheimer’s Disease

Cyclooxygenases (COX) are enzymes catalyzing arachidonic acid into prostanoids. COX exists in three isoforms: COX-1, 2, and 3. COX-1 and COX-2 have been widely studied in order to explore and understand their involvement in Alzheimer’s disease (AD), a progressive neuroinflammatory dementia. COX-2 wa...

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Detalles Bibliográficos
Autores principales: Tyagi, Arti, Kamal, Mohammad A., Poddar, Nitesh Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7364283/
https://www.ncbi.nlm.nih.gov/pubmed/32742252
http://dx.doi.org/10.3389/fnins.2020.00693