Single-cell lineage analysis reveals genetic and epigenetic interplay in glioblastoma drug resistance

BACKGROUND: Tumors can evolve and adapt to therapeutic pressure by acquiring genetic and epigenetic alterations that may be transient or stable. A precise understanding of how such events contribute to intratumoral heterogeneity, dynamic subpopulations, and overall tumor fitness will require experim...

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Detalles Bibliográficos
Autores principales: Eyler, Christine E., Matsunaga, Hironori, Hovestadt, Volker, Vantine, Samantha J., van Galen, Peter, Bernstein, Bradley E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7364565/
https://www.ncbi.nlm.nih.gov/pubmed/32669109
http://dx.doi.org/10.1186/s13059-020-02085-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7364565/
https://www.ncbi.nlm.nih.gov/pubmed/32669109
http://dx.doi.org/10.1186/s13059-020-02085-1

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