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SFRP1 increases TMPRSS2-ERG expression promoting neoplastic features in prostate cancer in vitro and in vivo

BACKGROUND: Prostate cancer (PCa) is the second cause of cancer related death in North American men. Androgens play an important role in its progression by regulating the expression of several genes including fusion ones that results from structural chromosome rearrangements. TMPRSS2-ERG is a fusion...

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Detalles Bibliográficos
Autores principales: Cruz-Hernández, Carlos D., Cruz-Burgos, Marian, Cortés-Ramírez, Sergio A., Losada-García, Alberto, Camacho-Arroyo, Ignacio, García-López, Patricia, Langley, Elizabeth, González-Covarrubias, Vanessa, Llaguno-Munive, Monserrat, Albino-Sánchez, Martha E., Cruz-Colín, José L., Pérez-Plasencia, Carlos, Beltrán-Anaya, Fredy O., Rodríguez-Dorantes, Mauricio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7364616/
https://www.ncbi.nlm.nih.gov/pubmed/32694934
http://dx.doi.org/10.1186/s12935-020-01333-5