Genome-wide DNA Methylation Signatures Are Determined by DNMT3A/B Sequence Preferences

[Image: see text] Cytosine methylation is an important epigenetic mark, but how the distinctive patterns of DNA methylation arise remains elusive. For the first time, we systematically investigated how these patterns can be imparted by the inherent enzymatic preferences of mammalian de novo DNA meth...

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Detalles Bibliográficos
Autores principales: Mao, Shi-Qing, Cuesta, Sergio Martínez, Tannahill, David, Balasubramanian, Shankar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7364778/
https://www.ncbi.nlm.nih.gov/pubmed/32543182
http://dx.doi.org/10.1021/acs.biochem.0c00339

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7364778/
https://www.ncbi.nlm.nih.gov/pubmed/32543182
http://dx.doi.org/10.1021/acs.biochem.0c00339

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