Cargando…

Genome-wide DNA Methylation Signatures Are Determined by DNMT3A/B Sequence Preferences

[Image: see text] Cytosine methylation is an important epigenetic mark, but how the distinctive patterns of DNA methylation arise remains elusive. For the first time, we systematically investigated how these patterns can be imparted by the inherent enzymatic preferences of mammalian de novo DNA meth...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mao, Shi-Qing, Cuesta, Sergio Martínez, Tannahill, David, Balasubramanian, Shankar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2020
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7364778/ https://www.ncbi.nlm.nih.gov/pubmed/32543182 http://dx.doi.org/10.1021/acs.biochem.0c00339

Ejemplares similares

DNA G-quadruplex structures mould the DNA methylome
por: Mao, Shi-Qing, et al.
Publicado: (2018)

DNMT3L Modulates Significant and Distinct Flanking Sequence Preference for DNA Methylation by DNMT3A and DNMT3B In Vivo
por: Wienholz, Bethany L., et al.
Publicado: (2010)

DNA sequence-dependent activity and base flipping mechanisms of DNMT1 regulate genome-wide DNA methylation
por: Adam, Sabrina, et al.
Publicado: (2020)

Sequencing abasic sites in DNA at single-nucleotide resolution
por: Liu, Zheng J., et al.
Publicado: (2019)

Mutations of R882 change flanking sequence preferences of the DNA methyltransferase DNMT3A and cellular methylation patterns
por: Emperle, Max, et al.
Publicado: (2019)

G-quadruplexes are transcription factor binding hubs in human chromatin
por: Spiegel, Jochen, et al.
Publicado: (2021)

RNA G-quadruplex structures control ribosomal protein production
por: Varshney, Dhaval, et al.
Publicado: (2021)

Structural Basis of DNMT1 and DNMT3A-Mediated DNA Methylation
por: Ren, Wendan, et al.
Publicado: (2018)

DSBCapture: in situ capture and direct sequencing of dsDNA breaks
por: Lensing, Stefanie V., et al.
Publicado: (2016)

Determinants of DNMT2/TRDMT1 preference for substrates tRNA and DNA during the evolution
por: Li, Huari, et al.
Publicado: (2023)

DNA Methylation Targeting: The DNMT/HMT Crosstalk Challenge
por: Castillo-Aguilera, Omar, et al.
Publicado: (2017)

G-Quadruplex structures are stable and detectable in human genomic DNA
por: Lam, Enid Yi Ni, et al.
Publicado: (2013)

DNMT inhibitors reverse a specific signature of aberrant promoter DNA methylation and associated gene silencing in AML
por: Lund, Kirstin, et al.
Publicado: (2014)

Stable DNMT3L overexpression in SH-SY5Y neurons recreates a facet of the genome-wide Down syndrome DNA methylation signature
por: Laufer, Benjamin I., et al.
Publicado: (2021)

The sequence preference of DNA methylation variation in mammalians
por: Zhang, Ling, et al.
Publicado: (2017)

Loss of spermatogonia and wide-spread DNA methylation defects in newborn male mice deficient in DNMT3L
por: La Salle, Sophie, et al.
Publicado: (2007)

The DNMT1-associated lincRNA DACOR1 reprograms genome-wide DNA methylation in colon cancer
por: Somasundaram, Saigopal, et al.
Publicado: (2018)

PGC7 Regulates Genome-Wide DNA Methylation by Regulating ERK-Mediated Subcellular Localization of DNMT1
por: Wei, Xing, et al.
Publicado: (2023)

Accuracy of DNA methylation pattern preservation by the Dnmt1 methyltransferase
por: Goyal, Rachna, et al.
Publicado: (2006)

Anchor-based bisulfite sequencing determines genome-wide DNA methylation
por: Chapin, Nathaniel, et al.
Publicado: (2022)

The inactive Dnmt3b3 isoform preferentially enhances Dnmt3b-mediated DNA methylation
por: Zeng, Yang, et al.
Publicado: (2020)

Chemical profiling of DNA G-quadruplex-interacting proteins in live cells
por: Zhang, Xiaoyun, et al.
Publicado: (2021)

Genome-Wide DNA Methylation Maps in Follicular Lymphoma Cells Determined by Methylation-Enriched Bisulfite Sequencing
por: Choi, Jeong-Hyeon, et al.
Publicado: (2010)

The USP7/Dnmt1 complex stimulates the DNA methylation activity of Dnmt1 and regulates the stability of UHRF1
por: Felle, Max, et al.
Publicado: (2011)

Efficient targeted DNA methylation with chimeric dCas9–Dnmt3a–Dnmt3L methyltransferase
por: Stepper, Peter, et al.
Publicado: (2017)

An Intramolecular G-Quadruplex Structure Is Required for Binding of Telomeric Repeat-Containing RNA to the Telomeric Protein TRF2
por: Biffi, Giulia, et al.
Publicado: (2012)

Genetic interactions of G-quadruplexes in humans
por: Zyner, Katherine G, et al.
Publicado: (2019)

DNMT1-interacting RNAs block gene specific DNA methylation
por: Di Ruscio, Annalisa, et al.
Publicado: (2013)

Characterization of Dnmt1 Binding and DNA Methylation on Nucleosomes and Nucleosomal Arrays
por: Schrader, Anna, et al.
Publicado: (2015)

Single-cell mapping of DNA G-quadruplex structures in human cancer cells
por: Hui, Winnie W. I., et al.
Publicado: (2021)

Correction: Genome-Wide DNA Methylation Maps in Follicular Lymphoma Cells Determined by Methylation-Enriched Bisulfite Sequencing
por: Choi, Jeong-Hyeon, et al.
Publicado: (2011)

∆ DNMT3B4-del Contributes to Aberrant DNA Methylation Patterns in Lung Tumorigenesis
por: Ma, Mark Z., et al.
Publicado: (2015)

Publisher Correction: Single-cell mapping of DNA G-quadruplex structures in human cancer cells
por: Hui, Winnie W. I., et al.
Publicado: (2022)

DNA METHYLATION BY DNMT1 AND DNMT3b METHYLTRANSFERASES IS DRIVEN BY THE MUC1-C ONCOPROTEIN IN HUMAN CARCINOMA CELLS
por: Rajabi, Hasan, et al.
Publicado: (2016)

DNMT3L facilitates DNA methylation partly by maintaining DNMT3A stability in mouse embryonic stem cells
por: Veland, Nicolas, et al.
Publicado: (2019)

Identification of distinct loci for de novo DNA methylation by DNMT3A and DNMT3B during mammalian development
por: Yagi, Masaki, et al.
Publicado: (2020)

DNMT1 regulates the timing of DNA methylation by DNMT3 in an enzymatic activity-dependent manner in mouse embryonic stem cells
por: Ito, Takamasa, et al.
Publicado: (2022)

Efficient and accurate determination of genome-wide DNA methylation patterns in Arabidopsis thaliana with enzymatic methyl sequencing
por: Feng, Suhua, et al.
Publicado: (2020)

FOXM1 binds directly to non-consensus sequences in the human genome
por: Sanders, Deborah A., et al.
Publicado: (2015)

Genome-wide DNA methylation reprogramming in response to inorganic arsenic links inhibition of CTCF binding, DNMT expression and cellular transformation
por: Rea, Matthew, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_uostsdqplbug4l2ff4v5rf0mb0