Enhanced Susceptibility to Chemoconvulsant-Induced Seizures in Ganglioside GM3 Synthase Knockout Mice

Ganglioside GM3 synthase (α-2,3-sialyltransferase, ST3GAL5, GM3S) is a key enzyme involved in the biosynthesis of gangliosides. ST3GAL5 deficiency causes an absence of GM3 and all downstream biosynthetic derivatives. The affected individuals manifest deafness, severe irritability, intractable seizur...

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Detalles Bibliográficos
Autores principales: Tang, Fu-Lei, Wang, Jing, Itokazu, Yukata, Yu, Robert K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7364800/
https://www.ncbi.nlm.nih.gov/pubmed/32664815
http://dx.doi.org/10.1177/1759091420938175

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7364800/
https://www.ncbi.nlm.nih.gov/pubmed/32664815
http://dx.doi.org/10.1177/1759091420938175

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