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Direct Phosphorylation of Psilocin Enables Optimized cGMP Kilogram-Scale Manufacture of Psilocybin

[Image: see text] A second-generation kilogram-scale synthesis of the psychedelic tryptamine psilocybin has been developed. The synthesis was designed to address several challenges first encountered with the scale-up of previously described literature procedures, which were not optimized for providi...

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Detalles Bibliográficos
Autores principales: Kargbo, Robert B., Sherwood, Alexander, Walker, Andrew, Cozzi, Nicholas V., Dagger, Raymond E., Sable, Jessica, O’Hern, Kelsey, Kaylo, Kristi, Patterson, Tura, Tarpley, Gary, Meisenheimer, Poncho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7364850/
https://www.ncbi.nlm.nih.gov/pubmed/32685866
http://dx.doi.org/10.1021/acsomega.0c02387