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MSI-2小干扰RNA对急性髓系白血病细胞株THP-1细胞增殖及NUMB表达的影响

OBJECTIVE: To investigate the effect of small interfering RNA (siRNA) for MSI-2 on the growth, apoptosis and NUMB expression of THP-1 cells. METHODS: Three siRNA for MSI-2 gene was designed and transfected into THP-1 cells. The cell inhibition, colony formation and apoptosis were determined. The pro...

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Detalles Bibliográficos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial office of Chinese Journal of Hematology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7364948/
https://www.ncbi.nlm.nih.gov/pubmed/26477766
http://dx.doi.org/10.3760/cma.j.issn.0253-2727.2015.10.011