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全反式维甲酸对NPM1突变的白血病细胞系U937细胞的作用及其机制研究

OBJECTIVE: To investigate the effect and mechanism of all-trans retinoic acid (ATRA) on leukemic cell line U937 cells with NPM1 mutation. METHODS: Human acute myeloid leukemia cell line U937 was explored, NPM1 mutated (A type) plasmids were transfected into U937 to form stable clones A1 and A2, whic...

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Detalles Bibliográficos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial office of Chinese Journal of Hematology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7364968/
https://www.ncbi.nlm.nih.gov/pubmed/29166739
http://dx.doi.org/10.3760/cma.j.issn.0253-2727.2017.10.008