靶向BCMA的嵌合抗原受体T细胞抗多发性骨髓瘤作用研究

OBJECTIVE: To construct the BCMA-CAR using the B-cell maturation antigen (BCMA) specific ligand APRIL as antigen binding region and to validate the effect of BCMA-CAR modified T cells (BCMA-CAR-T) on myeloma cells. METHODS: The BCMA-CAR was constructed using the BCMA specific ligand APRIL as antigen...

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Detalles Bibliográficos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial office of Chinese Journal of Hematology 2019
Materias:
论著
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7364977/
https://www.ncbi.nlm.nih.gov/pubmed/31775477
http://dx.doi.org/10.3760/cma.j.issn.0253-2727.2019.10.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7364977/
https://www.ncbi.nlm.nih.gov/pubmed/31775477
http://dx.doi.org/10.3760/cma.j.issn.0253-2727.2019.10.002

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