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靶向BCMA的嵌合抗原受体T细胞抗多发性骨髓瘤作用研究
OBJECTIVE: To construct the BCMA-CAR using the B-cell maturation antigen (BCMA) specific ligand APRIL as antigen binding region and to validate the effect of BCMA-CAR modified T cells (BCMA-CAR-T) on myeloma cells. METHODS: The BCMA-CAR was constructed using the BCMA specific ligand APRIL as antigen...
| Formato: | Online Artículo Texto |
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| Lenguaje: | English |
| Publicado: |
Editorial office of Chinese Journal of Hematology
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7364977/ https://www.ncbi.nlm.nih.gov/pubmed/31775477 http://dx.doi.org/10.3760/cma.j.issn.0253-2727.2019.10.002 |