Targeting Two-Pore Channels: Current Progress and Future Challenges

Two-pore channels (TPCs) are cation-permeable channels located on endolysosomal membranes and important mediators of intracellular Ca(2+) signalling. TPCs are involved in various pathophysiological processes, including cell growth and development, metabolism, and cancer progression. Most studies of...

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Detalles Bibliográficos
Autores principales: Jin, Xuhui, Zhang, Yuxuan, Alharbi, Abeer, Hanbashi, Ali, Alhoshani, Ali, Parrington, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7365084/
https://www.ncbi.nlm.nih.gov/pubmed/32679067
http://dx.doi.org/10.1016/j.tips.2020.06.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7365084/
https://www.ncbi.nlm.nih.gov/pubmed/32679067
http://dx.doi.org/10.1016/j.tips.2020.06.002

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