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Targeting Two-Pore Channels: Current Progress and Future Challenges
Two-pore channels (TPCs) are cation-permeable channels located on endolysosomal membranes and important mediators of intracellular Ca(2+) signalling. TPCs are involved in various pathophysiological processes, including cell growth and development, metabolism, and cancer progression. Most studies of...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Ltd.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7365084/ https://www.ncbi.nlm.nih.gov/pubmed/32679067 http://dx.doi.org/10.1016/j.tips.2020.06.002 |